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There are several matches for 'translation initiation factor 1'.
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5595 matches
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organism
protein
1)
Homo sapiens
EIF1B - Eukaryotic translation initiation factor 1b; Probably involved in translation.
[a.k.a. ENSG00000114784, NX_O60739, EAW64598.1,
Translation initiation factor 1
]
2)
Homo sapiens
EIF1 - Eukaryotic
translation
initiation
factor
1
; Necessary for scanning and involved in
initiation
site selection. Promotes the assembly of 48S ribosomal complexes at the authentic
initiation
codon of a conventional capped mRNA.
[a.k.a. ENST00000310837.8, AAP35291.1, EIF1-204,
Translation initiation factor 1
]
3)
Mus musculus
Eif1b - Eukaryotic translation initiation factor 1b; Probably involved in translation.
[a.k.a. MGI:1916219, Gc20, 1500010M16Rik,
Translation initiation factor 1
]
4)
Mus musculus
Eif1 - Eukaryotic
translation
initiation
factor
1
; Necessary for scanning and involved in
initiation
site selection. Promotes the assembly of 48S ribosomal complexes at the authentic
initiation
codon of a conventional capped mRNA (By similarity); Belongs to the SUI1 family.
[a.k.a. NM_011508, UPI000268B51E, AAH96656.1,
Translation initiation factor 1
]
5)
Drosophila melanogaster
eIF1 - Eukaryotic translation initiation factor eIF1; Probably involved in translation.
[a.k.a. FBgn0035423, eIF1-PA, EIF1,
Translation initiation factor 1
]
6)
Caenorhabditis elegans
eif-1 - SUI1 domain-containing protein.
[a.k.a. T27F7.3, CELE_T27F7.3, WBGene00020868,
Translation initiation factor 1
]
7)
Escherichia coli K12
yciH - Initiation factor function partial mimic, SUI1 family; Belongs to the SUI1 family.
[a.k.a. b1282, AAC74364.2, P08245,
Translation initiation factor 1
]
8)
Saccharomyces cerevisiae
SUI1 - Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase; Belongs to the SUI1 family.
[a.k.a. YNL244C, 2RVH, AAA35131.1,
Translation initiation factor 1
]
9)
Homo sapiens
EIF4EBP1 - Eukaryotic
translation
initiation
factor
4E-binding protein
1
; Repressor of
translation
initiation
that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress
translation
. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to
initiation
of
translation
. Mediates the regulation of protein
translation
by hormones, growth
factors
and other stimuli that signal through the MAP kinase and mTORC1 pathways.
[a.k.a. uc003xks.4, R-HSA-72737, 4EBP1]
10)
Homo sapiens
EIF2AK1 - Eukaryotic
translation
initiation
factor
2-alpha kinase
1
; Inhibits protein synthesis at the
translation
initiation
level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a
1
:
1
complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...]
[a.k.a. ENSP00000392459, ENST00000463213.5, UPI000173A260]
11)
Homo sapiens
EIF4G1 - Eukaryotic
translation
initiation
factor
4 gamma
1
; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome; Belongs to the eukaryotic
initiation
factor
4G family.
[a.k.a. R-HSA-72737, ENST00000434841, ENST00000475721]
12)
Homo sapiens
YTHDF1 - YTH domain-containing family protein
1
; Specifically recognizes and binds N6-methyladenosine (m6A)- containing mRNAs, and promotes mRNA
translation
efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA
translation
efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with
translation
initiation
factors
eIF3 (EIF3A or EIF3B) to facilitate
translation
initiation
. Required to facilitate learning and memory formation in the [...]
[a.k.a. ENST00000370339, YTH domain family, member 1, 4RCI]
13)
Homo sapiens
EIF2S1 -
translation
initiation
factor
2 subunit
1
; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and
initiator
tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-
initiation
complex. Junction of the 60S ribosomal subunit to form the 80S
initiation
complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of
initiation
, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction
[a.k.a. R-HSA-72737, ENST00000555876, ENSG00000134001]
14)
Homo sapiens
PPP1R15A - Protein phosphatase
1
regulatory subunit 15A; Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the
translation
initiation
factor
eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis
initiated
by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
[a.k.a. R-HSA-170834, 23645, R-HSA-162582]
15)
Homo sapiens
RPS6KB1 - Ribosomal protein S6 kinase beta-1; Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth
factors
and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3
translation
initiation
complex. Upon mitogenic stimulation, phosphorylation by the mammalian target of rapamycin complex
1
(mTO [...]
[a.k.a. NP_001356601.1, URS0000EACB8A, 4L43]
16)
Mus musculus
Eif4ebp1 - Eukaryotic
translation
initiation
factor
4E-binding protein
1
; Repressor of
translation
initiation
that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress
translation
. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to
initiation
of
translation
(By similarity). Mediates the regulation of protein
translation
by hormones, growth
factors
and other stimuli that signal through the MAP kinase a [...]
[a.k.a. UPI00000237BD, AA959816, PHAS-I]
17)
Mus musculus
Eif2ak1 - Eukaryotic
translation
initiation
factor
2-alpha kinase
1
; Inhibits protein synthesis at the
translation
initiation
level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser- 51', thus preventing its recycling. Binds hemin forming a
1
:
1
complex through a cysteine thiolate and histidine nitrogenous coordination. This binding occurs with moderate affinity, allowing it to sense the heme concentration within the cell. Thanks to this unique heme-se [...]
[a.k.a. NP_038585, Hri, ENSMUST00000100487.5]
18)
Mus musculus
Ythdf1 - YTH domain-containing family protein
1
; Specifically recognizes and binds N6-methyladenosine (m6A)- containing mRNAs, and promotes mRNA
translation
efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA
translation
efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with
translation
initiation
factors
eIF3 (EIF3A or EIF3B) to facilitate
translation
initiation
(By similarity). Required to facilitate learning and memory [...]
[a.k.a. NM_173761.3, ENSMUSG00000038848, BC065050]
19)
Mus musculus
Eif2s1 -
translation
initiation
factor
2 subunit
1
; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and
initiator
tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-
initiation
complex. Junction of the 60S ribosomal subunit to form the 80S
initiation
complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of
initiation
, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction
[a.k.a. Eif2s1-201, NP_080390, R-MMU-381119]
20)
Mus musculus
Eif4g1 - Eukaryotic
translation
initiation
factor
4 gamma
1
; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.
[a.k.a. UPI00064547C7, ENSMUSP00000143861, ENSMUST00000156226.7]
5595 matches
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